Goiter and Sensorineural Hearing Loss: Pendred Syndrome Should Be Suspected: A Case Report
Sana Mallouk,
Zouhair Najib,
Omar Iziki,
Youssef Oukessou,
Sami Rouad,
Reda Abada,
Mohamed Mahtar,
Mohamed Roubal
Issue:
Volume 6, Issue 2, December 2020
Pages:
23-25
Received:
20 March 2020
Accepted:
7 May 2020
Published:
13 July 2020
Abstract: BACKGROUND: Pendred syndrome (PS) is an autosomal recessive disorder, caused by biallelic mutations in the SLC26A4 gene which codes for the pendrin protein. It is characterized by sensorineural hearing loss associated with dyshormonogenic goiter. Which is a common cause of congenital deafness. CASE PRESENTATION: Hereby we describe a case of a 21- year-old women who presented to the ORL department with an anterior cervical mass that gradually increased in volume over 3 years associated with severe hearing loss since birth for which the patient was provided with hearing aids. Pendred syndrome is suspected because of the present of goiter and congenital hearing loss. CONCLUSIONS: Clinical presentation is very variable. However, the association of goiter and progressive deafness suggests the diagnosis of Pendred syndrome.
Abstract: BACKGROUND: Pendred syndrome (PS) is an autosomal recessive disorder, caused by biallelic mutations in the SLC26A4 gene which codes for the pendrin protein. It is characterized by sensorineural hearing loss associated with dyshormonogenic goiter. Which is a common cause of congenital deafness. CASE PRESENTATION: Hereby we describe a case of a 21- y...
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Conductive Hearing Loss with an Intact Tympanic Membrane: Diagnosed Approaches
Sana Mallouk,
Sara Halily,
Yasser Hammouda,
Youssef Oukessou,
Sami Rouadi,
Reda Abada,
Mohamed Mahtar,
Mohamed Roubal
Issue:
Volume 6, Issue 2, December 2020
Pages:
26-30
Received:
5 August 2020
Accepted:
17 August 2020
Published:
16 September 2020
Abstract: Objective: Our study aims to analyze the epidemiological, clinical, radiological, and etiological aspects of this disease. Methods: We reviewed data from patients who consulted the same seigneur for hearing loss and in whom the otoscopic examination was normal with a conductive hearing loss objectively confirmed on tonal audiometry, for a period of one year (from October 2018 to October 2019). Epidemiological, clinical and paraclinical data were collected and recorded on-farm records. Results: The average age is 36 years. The M/F sex ratio was 1.5 in favor of the men. None of our patients reported a personal otologic history. Three patients reported a notion of head trauma and a similar case in the family was found in four patients. Hearing loss is the most frequent reason for consultation. Otoscopic examination shows a normal tympanic membrane without perforation in all patients. CT scan of the temporal bone was performed in all patients (100%); it was normal in 4 cases (17%), which required surgical exploration. However, he showed images of otosclerosis in 15 cases (65%), an image of congenital cholesteatoma in a single patient, tympanic glomus in a single patient, an incudo-malleolar dislocation in a single patient (4.5%), and an incudo-stapedial dislocation in a single patient (4.5%). Conclusion: Conductive hearing loss (CHL) is a diagnostic challenge for the physician that requires a schematic approach. The diagnosis is based on a combination of clinical and paraclinical arguments.
Abstract: Objective: Our study aims to analyze the epidemiological, clinical, radiological, and etiological aspects of this disease. Methods: We reviewed data from patients who consulted the same seigneur for hearing loss and in whom the otoscopic examination was normal with a conductive hearing loss objectively confirmed on tonal audiometry, for a period of...
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Laryngeal Stenosis, a Complication of Multifocal Tuberculosis
Samaké Djibril,
Sidibé Youssouf,
Dienta Lassine,
Haidara Abdoul,
Kouma Alassane,
Touré Mamadou Karim,
Ouattara Kadidia,
Kanouté Tenin,
Soumaoro Siaka,
Guindo Boubacary,
Traoré Lamine,
Sanogo Boubacar,
Keita Mohamed Amadou,
Ag Mohamed Alhousseini
Issue:
Volume 6, Issue 2, December 2020
Pages:
31-34
Received:
21 August 2020
Accepted:
3 September 2020
Published:
30 September 2020
Abstract: Laryngeal stenosis is a permanent, usually acquired, narrowing of the laryngeal duct. Due to the pandemic of Acquired Immunodeficiency Syndrome (AIDS), the etiology of tuberculosis must be investigated. However, the signs of presumption are not specific. Management is controversial and remains difficult in our work context in an under-medicated country south of the Sahara. The purpose of the work is to report a case of laryngeal stenosis secondary to multifocal tuberculosis to discuss the difficulties associated with its management. This was a 35-year-old smoking patient with 25 packs / year. Admitted on 04/12/2017 to the ENT and Head and Neck Surgery Department for assessment of dysphonia associated with unencrypted slimming. The performed laryngoscopy showed disseminated ulceration of the laryngeal margin, and the histology showed granulomatous laryngitis. The intradermal reaction to tuberculin measured 10 mm. A chest X-ray performed on the face showed a chronic interstitial-bronchial syndrom. The diagnosis of laryngeal tuberculosis secondary to a pulmonary focus was retained. The course was marked by the sudden onset of laryngeal dyspnea requiring urgent tracheotomy. Postoperative examination of the larynx revealed synechia of the larynx. Anti-tuberculosis therapy for six months has resulted in favourable outcomes. However, it was noted a complication type laryngeal stenosis despite the attempted re-stabilization with impossibility to decant the patient. Laryngeal stenosis secondary to multifocal tuberculosis remains a rare and dreadful pathology. Therapeutic success depends on early and adequate management.
Abstract: Laryngeal stenosis is a permanent, usually acquired, narrowing of the laryngeal duct. Due to the pandemic of Acquired Immunodeficiency Syndrome (AIDS), the etiology of tuberculosis must be investigated. However, the signs of presumption are not specific. Management is controversial and remains difficult in our work context in an under-medicated cou...
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